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Lonidamine: A Hyperthermic Sensitizer of HeLa Cells in Culture and of the Meth-A Tumor in vivo

 

作者: J.H. Kim,   Sang Hie Kim,   Alan Alfieri,   Charles W. Young,   Bruno Silvestrini,  

 

期刊: Oncology  (Karger Available online 1984)
卷期: Volume 41, issue 1  

页码: 30-35

 

ISSN:0030-2414

 

年代: 1984

 

DOI:10.1159/000225882

 

出版商: S. Karger AG

 

关键词: Lonidamine;Hyperthermia;HeLa cells;Murine Meth-A tumor

 

数据来源: Karger

 

摘要:

Lonidamine was studied in HeLa cell cultures and BALB/c mice with Meth-A fibrosarcoma. Lonidamine is a hyperthermia sensitizer, both in vivo and in vivo. In vitro the potentiating effects were higher at low pH conditions.

 

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