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The Chocuhaler: sweet deliverance in asthma management

 

作者: Mark J Hayden,   Johannes H Wildhaber,   Ernst Eber,   Sunalene G Devadason,  

 

期刊: Medical Journal of Australia  (WILEY Available online 1995)
卷期: Volume 163, issue 11-12  

页码: 587-588

 

ISSN:0025-729X

 

年代: 1995

 

DOI:10.5694/j.1326-5377.1995.tb124760.x

 

出版商: Wiley

 

数据来源: WILEY

 

摘要:

ObjectiveTo determine the characteristics of a new cocoa‐based edible spacer device for the delivery of aerosol bronchodilator.DesignIn‐vitro comparison of two spacer devices (standard and edible) and determination of bronchodilator response using the edible spacer.SettingA university children's hospital in Western Australia.SubjectsTwo volunteers with moderate asthma.ResultsCompared with a standard spacer, the edible spacer delivered significantly more bronchodilator in droplets of a size likely to enter the respiratory tract. A significant bronchodilator response occurred in two out of two subjects when salbutamol was inhaled orally via the chocolate spacer. No significant bronchodilator response occurred in either subject when the spacer was eaten at the end of the study.ConclusionThe chocolate spacer used in this study is a suitable device to deliver salbutamol by inhalation. However, there may be potential drawbacks of weight gain in some patients and meltdown in hot climates.

 

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