Gepirone in AnxietyA Pilot Study
作者:
IRMA,
CSANALOSI EDWARD,
SCHWEIZER KARL,
RICKELS WARREN,
期刊:
Journal of Clinical Psychopharmacology
(OVID Available online 1987)
卷期:
Volume 7,
issue 1
页码: 31-32
ISSN:0271-0749
年代: 1987
出版商: OVID
数据来源: OVID
摘要:
Ten patients suffering from generalized anxiety disorder were treated, after a single-blind placebo washout week, with the nonbenzodiazepine anxiolytic gepirone in a 6-week open label trial. Mean Hamilton Anxiety scores improved from 24.8 to 7.1 (p< 0.01). Other physician- and patient-rated scales showed comparable improvement on a mean maximal dose of 41 mg of gepirone. The medication appeared to be nonsedating and well tolerated. The anxiolytic effect of the medication was very marked in several cases, and gepirone appears to have promise as an anxiolytic agent.
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