Non‐A Non‐B Hepatitis and the Safety of Intravenous Immune Globulin, pH 4.2: A Retrospective Survey:
作者:
Ralph H. Rousell,
Robert A. Good,
Bernard Pirofsky,
Richard I. Schiff,
期刊:
Vox Sanguinis
(WILEY Available online 1988)
卷期:
Volume 54,
issue 1
页码: 6-13
ISSN:0042-9007
年代: 1988
DOI:10.1111/j.1423-0410.1988.tb01605.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
Abstract.Evidence for transmission of non‐A non‐B hepatitis (NANB) was sought in 41 patients with primary immune deficiency who were receiving human intravenous immune globulin (IGIV) over periods ranging from 6 to 15 months at a monthly dosage of 400 mg/kg body weight. One lot of a reduced and alkylated IGIV and three lots of a nonmodified preparation stabilized at pH 4.2 were used. No evidence of NANB was found, although transient elevations in serum glutamic pyruvic transaminase (alanine aminotransferase) were found in 6 of the patients. The possible causes of the elevated levels in these 6 patients are discus
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