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Radioimmunodetection of Tumors with Monoclonal Antiplacental Ferritin Antibody: Preliminary Results

 

作者: C. Moroz,   Z. Lantsberg,   O. Sela,   Y. Cohen,   J. Khodadadi,   J. Goldstein,   M.R. Quastel,   Y. Shoenfeld,  

 

期刊: Oncology  （Karger Available online 1989）
卷期: Volume 46, issue 1  

页码: 35-39

 

ISSN:0030-2414

 

年代: 1989

 

DOI:10.1159/000226677

 

出版商: S. Karger AG

 

关键词: Ferritin;Antiferritin antibodies;Hepatoma;Breast carcinoma

 

数据来源: Karger

 

摘要:

Two mouse monoclonal antiferritin antibodies were employed to detect tumors. In the first case a solitary hepatoma was defined, while in the second one, mediastinal metastases of breast cancer were detected. In both cases serum ferritin levels were raised. The availability of monoclonal antiferritin antibodies offers certain advantages over polyclonal antibodies (ease of production, purification and reproducibility). These antiferritin antibodies may be found useful in diagnosis and therapy of certain tumors.

 

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