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Site of expression of immunity to Naegleria fowled in immunized mice

 

作者: Y. H. THONG,   R‐F. CARTER,   A. FERRANTE,   B. ROWAN‐KELLY,  

 

期刊: Parasite Immunology  （WILEY Available online 1983）
卷期: Volume 5, issue 1  

页码: 67-76

 

ISSN:0141-9838

 

年代: 1983

 

DOI:10.1111/j.1365-3024.1983.tb00724.x

 

出版商: Blackwell Publishing Ltd

 

关键词: Naegleria fowleri;immunized mice;protection;histology;nasal mucosa;inflammation;polymorphs;epithelium shedding

 

数据来源: WILEY

 

摘要:

SummaryAn experiment was performed which confirmed a previous finding that mice are protected against Naegleria fowleri infection by immunization with amoeba‐free supernatant from amoeba cultures. Histological observations suggested that this protection is expressed mainly at the nasal mucosa and possibly results from the combined effects of polymorphonuclear leucocyte‐mediated killing of the amoeba and mechanical elimination of the organisms by extensive shedding of necrotic epithel

 

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