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Prenatal effects of ochratoxin a in hamsters

 

作者: Ronald D. Hood,   Michael J. Naughton,   A. Wallace Hayes,  

 

期刊: Teratology  (WILEY Available online 1976)
卷期: Volume 13, issue 1  

页码: 11-14

 

ISSN:0040-3709

 

年代: 1976

 

DOI:10.1002/tera.1420130103

 

出版商: Wiley Subscription Services, Inc., A Wiley Company

 

数据来源: WILEY

 

摘要:

AbstractPregnant golden hamsters were injected ip with 2.5–20 mg/kg ochratoxin A on one of gestation days 7–10. The largest dosages when given on day 7, 8, or 9 increased prenatal mortality and on day 9 diminished fetal growth. Malformations, such as micrognathia, hydrocephalus, short tail, oligodactyly, syndactyly, cleft lip, micromelia, and heart defects occurred, but no skeletal malformations were noted. These results add to the prenatal effects of ochratoxin A previously reported in mouse, rat, and chicken embr

 

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