Herpes simplex hepatitis with chronic cholestasis in a newborn
作者:
S Marret,
C Buffet‐Janvresse,
J Metayer,
C Fessard,
期刊:
Acta Pædiatrica
(WILEY Available online 1993)
卷期:
Volume 82,
issue 3
页码: 321-323
ISSN:0803-5253
年代: 1993
DOI:10.1111/j.1651-2227.1993.tb12673.x
出版商: Blackwell Publishing Ltd
关键词: Acyclovir;cholestasis;hepatitis;herpes simplex;newborn
数据来源: WILEY
摘要:
In the case of the central nervous system or hepatic involvement, the prognosis of neonatal herpes simplex infection remains poor, despite antiviral drugs, presumably effective if given early. We report the case of a neonate with herpes simplex hepatitis, where the course of the illness was unusual with chronic, ultimately fatal, cholestasis. The treatment was not effective, because its administration was delayed, because of high infant C reactive protein level and the absence of clinical maternal genital infection, and because it was interrupted due to misleading information: clinical improvement, negative viral tests and raised herpes IgG antibody titer.
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