Mortality From Heart Disease Among Workers Exposed to Solvents
作者:
Timothy Wilcosky,
Herman Tyroler,
期刊:
Journal of Occupational Medicine
(OVID Available online 1983)
卷期:
Volume 25,
issue 12
页码: 879-885
ISSN:0096-1736
年代: 1983
出版商: OVID
数据来源: OVID
摘要:
Several rubber industry jobs that are associated with cardiovascular disease (CVD) mortality involve the use of solvents and, since the only known occupational cause of atherosclerosis is a solvent (carbon disulfide), solvent exposures may contribute to the CVD excess observed among rubber industry workers. Detailed exposure estimates for 25 solvents were available for a cohort of 1,282 white male production workers in a large rubber- and tire-manufacturing plant, and a survivorship analysis compared the CVD mortality experience of exposed and nonexposed workers during a 15-year follow-up period. The known association between carbon disulfide exposure and ischemic heart disease (IHD) was apparent among these workers, and two other solvents, ethanol and phenol, were also found to be significant predictors of IHD. These exploratory findings suggest that solvents other than carbon disulfide may cause atherosclerotic disease.
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