Effects of 1% chlorhexidine gel treatment on sympathetic adrenergic nerves in human buccal mucosa
作者:
JOHAN LUTHMAN,
ANDREAS HENSCHEN,
HELÉNE LÖHÖNEN,
期刊:
European Journal of Oral Sciences
(WILEY Available online 1986)
卷期:
Volume 94,
issue 1
页码: 47-49
ISSN:0909-8836
年代: 1986
DOI:10.1111/j.1600-0722.1986.tb01362.x
出版商: Blackwell Publishing Ltd
关键词: adrenergic innervation;chlorhexidine gel;mucosa, oral
数据来源: WILEY
摘要:
Abstract –The effect of treatment with a commercially available 1 % chlorhexidine gel (Hibitane Dental) in custom trays for 14 days (10 min daily) on the sympathetic adrenergic nerves in biopsies from human buccal mucosa was investigated. Chemical assay of endogenous noradrenaline concentration and immunocytochemical demonstration of tyrosine hydroxylase served as markers for structural and functional integrity of the adrenergic nerves. The mean concentration of noradrenaline in chlorhexidine treated tissues did not differ from the mean concentration in control. No morphologic or fluorescence intensity differences of the tyrosine hydroxylase immunoreactivity were found in the chlorhexidine treated tissues when compared to controls. These findings indicate that a relatively intense treatment with a commercially available 1% chlorhexidine gel does not affect the adrenergic innervation of human buccal mucos
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