Der Hautvasokonstriktionstest am Menschen als Prüfmethode für Externcorticoide
作者:
Ulrike Lutz,
Erich G. Weirich,
期刊:
Dermatology
(Karger Available online 1974)
卷期:
Volume 148,
issue 3
页码: 160-174
ISSN:1018-8665
年代: 1974
DOI:10.1159/000251617
出版商: S. Karger AG
关键词: Topical corticoids;Skin vasoconstriction assay
数据来源: Karger
摘要:
The fact that many modifications of the technique originally elaborated by Mckenzie and Stoughton for skin vasoconstriction assay have been introduced considerably complicates the task of making a comparative appraisal of the methods used and the results obtained. Despite the large sources of variance, the rank orders of most topical corticoids obtained in tests carried out according to widely varying techniques by many different investigators are relatively consistent. An effort should be made to achieve a higher degree of concordance between different investigators – which applies also to the rank intervals and absolute potency values – by devising and adhering to a standardized proced
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