Epirubicin Weekly in Combination Chemotherapy with Cyclophosphamide and Vincristin in Untreated Small Cell Lung Cancer: A Phase II Trial
作者:
A. Kretzschmar,
P. Drings,
期刊:
Onkologie
(Karger Available online 1990)
卷期:
Volume 13,
issue 2
页码: 141-142
ISSN:0378-584X
年代: 1990
DOI:10.1159/000216742
出版商: S. Karger GmbH
关键词: Small cell lung carcinoma;Epirubicin weekly with cyclophosphamide and vincristine
数据来源: Karger
摘要:
Thirty-three patients with untreated small cell lung carcinoma received 6 cycles epirubicin 30 mg/m2 i.v. on days 1, 8, and 15, in combination with cyclophosphamide 1,000 mg/m2 on day 1 and vincris-tine 2 mg i.v. on day 1 every 3 weeks. Thirty-one patients were evaluable concerning state of remission. Four out of 13 patients with limited disease had a complete, and 6 a partial remission, while 2 out of 18 patients with extensive disease had a complete and 8 a partial remission. The toxicity of this therapy regimen was very low. The results of this treatment did not differ significantly in comparison to the standardized treatment of small cell lung cancer, but it was easier to tolerate.
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