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Pregnancy-Associated Idiopathic Intrahepatic Cholestasis

 

作者: L. Marpeau,   O. Chazouillière,   Z. Rhimi,   R. Poupon,   A. Pigne,   J. Barrat,  

 

期刊: Fetal Diagnosis and Therapy  （Karger Available online 1991）
卷期: Volume 6, issue 3-4  

页码: 120-125

 

ISSN:1015-3837

 

年代: 1991

 

DOI:10.1159/000263635

 

出版商: S. Karger AG

 

关键词: Biliary acids;Ursodesoxycholic acid;Idiopathic intrahepatic cholestasis

 

数据来源: Karger

 

摘要:

By modification of the circulating pool of biliary acids, the administration of ursodesoxycholic acid has permitted the restoration of normal maternal hepatic function during a triple pregnancy complicated by the precocious onset of an intrahepatic cholestasis. The marked regression in clinical and biological markers of the disease confirms the role of biliary acids in the aggravation of hepatic abnormalities.

 

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