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Polypeptide Fraction from Bovine Factor VIII Used in Fluorangiography

 

作者: P. Ammannati,   D. Siravo,   G.B. Gervasi,   E. Gelso,   M. Baldacci,  

 

期刊: Ophthalmologica  （Karger Available online 1988）
卷期: Volume 197, issue 1  

页码: 51-55

 

ISSN:0030-3755

 

年代: 1988

 

DOI:10.1159/000309918

 

出版商: S. Karger AG

 

关键词: Fluorescein angiography;Bovine-factor-VΠI-derived polypeptide;FITC-polypeptide fraction

 

数据来源: Karger

 

摘要:

We report a new method of fluorangiography employing a polypeptide fraction from bovine factor VIII that has shown remarkable affinity to the endothelial surface of microvessels. Rabbits injected with this compound, labeled with fluorescein isothiocyanate, show a very delayed dissappearance time of fluorescence in retinal vessels when compared with those injected with ordinary fluorescein. This allows a good observation of the late time, which is of great diagnostic advantage for several pathological conditions.

 

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