Comparison of T Helper/T Suppressor Ratios in Aqueous Humor and Blood Samples by Flow Cytometric Analysis
作者:
Avni Murat Avunduk,
Kubilay Çetinkaya,
Zerrin Kapicioğlu,
期刊:
Ophthalmologica
(Karger Available online 1997)
卷期:
Volume 211,
issue 2
页码: 84-86
ISSN:0030-3755
年代: 1997
DOI:10.1159/000310764
出版商: S. Karger AG
关键词: Aqueous humor;Anterior chamber-associated;immune deviation;T helper lymphocyte;T suppressor lymphocyte
数据来源: Karger
摘要:
This study investigates the T lymphocyte role in the production of the specific immunosuppressive environment that occupies the anterior segment of the eye. Aqueous and peripheral venous blood samples were taken from 23 patients who were operated because of senile cataract. In all samples, T helper/T suppressor ratios were established and differences between aqueous and blood samples were investigated by t statistic and Mann-Whitney U test. We found significantly more T suppressor cell activity in aqueous humor than in peripheral blood (p < 0.05). We think that high T suppressor concentration in aqueous humor plays an important role in the induction of the immunosuppressive microenvironment that occupies the anterior chamber of the eye.
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