Treatment of Chronic Suppurated Otitis with Fosfomycin
作者:
J.M. Sole Puyo,
R. Poch Viñals,
期刊:
Chemotherapy
(Karger Available online 1977)
卷期:
Volume 23,
issue 1
页码: 379-391
ISSN:0009-3157
年代: 1977
DOI:10.1159/000222079
出版商: S. Karger AG
关键词: Fosfomycin;Chronic otitis
数据来源: Karger
摘要:
A group of 24 patients with suppurated chronic processes of the medial ear have been treated with fosfomycin. All the cases were studied bacteriologically, isolating in the pus or exudates pathogenic bacterial flora, in which P. aeruginosa (40% of the isolations) and S. aureus (23%) predominated. The sensitiveness of the strains isolated to fosfomycin was 94%. The results obtained were 21 clinical cures accompanied by the sterility of the exudates and 3 failures, which represents 87.5% success and 12.5% failures. These results are considered very satisfactory in view of the complexity and chronicity of the processes treated. It is also pointed out that fosfomycin totally lacks ototoxicity, being, therefore, a suitable antibiotic for treating chronic infectious processes of the ear.
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