Reticular erythematous mucinosis: light and electron microscopy, irnmunofluorescence and histochemical findings
作者:
S.S. BLEEHEN,
D.N. SLATER,
J. MAHOOD,
R.E. CHURCH,
期刊:
British Journal of Dermatology
(WILEY Available online 1982)
卷期:
Volume 106,
issue 1
页码: 9-18
ISSN:0007-0963
年代: 1982
DOI:10.1111/j.1365-2133.1982.tb00896.x
出版商: Blackwell Publishing Ltd
数据来源: WILEY
摘要:
SUMMARYFive patients with reticular erythematous mucinosis were studied by skin biopsy and phototesting. Light microscopy showed a dermal mononuclear cell infiltrate (composed largely of lymphocytes), separation of collagen bundles and fragmentation of elastic fibres. Histochemical stains showed increased dermal mucin with a profile consistent with hyaluronic acid. In one case, the ultrastructural distribution of mucin was demonstrated using colloidal iron staining, electron microscopy and X‐ray microanalysis. In two cases, virus‐like tubular aggregates were identified in the cytoplasm of dermal cndothclial cells and pericytes. Immunofluorescent staining for immunoglobulins, fibrin and complement was negat
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