Cardiovascular disease (CVD) is the leading cause of death among Americans. Although efforts have been made to educate the public on CVD risk factors, gaps may still exist between information dissemination and application in people's lives. To determine if CVD knowledge is related to CVD risk-reducing behaviors, 187 adults were surveyed using a questionnaire developed to assess CVD knowledge and health-related behaviors. No associations existed between knowledge and having cholesterol and blood pressure examinations, suggesting that, in this population, CVD knowledge alone does not translate into health-related practices aimed at reducing CVD risk.