Cytochemical Demonstration of Actin Filaments in Myoepithelial Cells of the Human Parotid Gland
作者:
Toshio Yoshihara,
Takashi Kanda,
Hiroshi Nagata,
Minoru Nomoto,
Toshio Kaneko,
Yuichi Kato,
Yuji Yaku,
期刊:
Cells Tissues Organs
(Karger Available online 1988)
卷期:
Volume 132,
issue 4
页码: 317-320
ISSN:1422-6405
年代: 1988
DOI:10.1159/000146594
出版商: S. Karger AG
关键词: Actin filament;Heavy meromyosin;Myoepithelial cell;Parotid gland;Human
数据来源: Karger
摘要:
Ultrastructurally, myoepithelial cells were shown to contain numerous fine filaments in their cytoplasm and resembled smooth muscle cells. The myoepithelial cell of the salivary gland has been considered to play an important role in the secretion of saliva. The present study showed that all the thin filaments (actin filaments) in the myoepithelial cell of the human parotid gland bound heavy meromyosin (HMM) and formed characteristic arrowhead structures. These filaments ran in two opposite directions with the poles at different ends. On the other hand, there was no binding of HMM with thicker filaments (10-nm filaments), plasma membrane, nuclear membrane, collagen fibrils, basement membrane or other cytoplasmic organelles.The present results strongly suggest that myoepithelial cells possess a contractile function parallel to the long axis of the cell for supporting the secretion of saliva in the parotid gland.
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