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Intranuclear Particles in Keratoacanthoma: Possible Association with Malignant Degeneration

 

作者: W.J.B.M. van de Staak,   A.M.G. Bergers,  

 

期刊: Dermatology  （Karger Available online 1979）
卷期: Volume 158, issue 6  

页码: 413-416

 

ISSN:1018-8665

 

年代: 1979

 

DOI:10.1159/000250791

 

出版商: S. Karger AG

 

关键词: Keratoacanthoma;Intranuclear virus-like particles

 

数据来源: Karger

 

摘要:

Electron microscopic investigation of 12 patients with keratoacanthoma is reported. Intranuclear virus-like particles, as described by Zelickson and Lynch, were seen in 3 cases; 2 of these subsequently underwent malignant degeneration. These findings suggest that it is particularly important to exclude the possibility of malignant change in those tumours when intranuclear particles are found.

 

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