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Human Phosphoglucomutase Locus 1: Red Cell Enzymatic Activities Associated with Common Isoelectric Focusing Phenotypes

 

作者: Renato Scacchi,   Rosa Maria Corbo,   Ricciotti Palmarino,   Gianna Sacco,   Michele Arnone,   Paola Lucarelli,  

 

期刊: Human Heredity  （Karger Available online 1983）
卷期: Volume 33, issue 4  

页码: 218-222

 

ISSN:0001-5652

 

年代: 1983

 

DOI:10.1159/000153381

 

出版商: S. Karger AG

 

关键词: Phosphoglucomutase;Isoelectric focusing;Enzyme activity;Electrophoretic variation

 

数据来源: Karger

 

摘要:

Human phosphoglucomutase activity has been determined in red blood cells obtained from 348 unrelated subjects. The mean activities attributed to the four common PGM1 alleles, expressed as micromoles of G6P produced per gram of Hb per hour were 53 for PGMa13, 60 for PGMa11, 61 for PGMa14 and 72 for PGMa12. The relative amount of variation associated with the electrophoretic polymorphism was estimated as 24%.

 

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