Paget's Disease of the Vulva and Carcinoma of the Breast
作者:
EDUARD FRIEDRICH,
EDWARD WILKINSON,
PAUL STEINGRAEBER,
J DAVID LEWIS,
期刊:
Obstetrics & Gynecology
(OVID Available online 1975)
卷期:
Volume 46,
issue 2
页码: 130-134
ISSN:0029-7844
年代: 1975
出版商: OVID
数据来源: OVID
摘要:
Vulvar Paget's disease is an intraepithelial change which is locally recurrent and has minimal if any propensity to invasion. Its major significance lies in the frequency with which concomitant carcinomas are discovered in association with the vulvar skin lesion. Adenocarcinoma of the vulvar apocrine glands is the most commonly associated tumor. Another apocrine adenocarcinoma, carcinoma of the breast, either antecedent or concomitant, is the second most frequently associated tumor, having been noted in 14 cases of vulvar Paget's disease. A case report illustrating this association is presented, and the importance of preoperative breast screening procedures in all patients with vulvar Paget's disease is demonstrated.
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