A Rabbit Model of Endometriosis
作者:
G.A.J. Dunselman,
D. Willebrand,
J.A. Land,
P.X.J.M. Bouckaert,
J.L.H. Evers,
期刊:
Gynecologic and Obstetric Investigation
(Karger Available online 1989)
卷期:
Volume 27,
issue 1
页码: 29-33
ISSN:0378-7346
年代: 1989
DOI:10.1159/000293611
出版商: S. Karger AG
关键词: Endometriosis;Animal model;Adhesions
数据来源: Karger
摘要:
Since not all problems in endometriosis can be studied in the human, there is need of an animal model. We transplanted endometrial tissue of the rabbit into the peritoneal cavity and studied the changes after 12 weeks. At that time the endometrial implants in the rabbit had become cystic structures. The macroscopic and histologic appearance was consistent with endometriosis. Hormonal supplementation turned out not to be necessary. Microsurgical techniques prevented the formation of tubo-ovarian adhesions. This makes the rabbit model suitable for studying the influence of endometrial implants on fertility.
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