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Cholinomimetic teratogens. III. Interaction with amino acids known as neurotransmitters

 

作者: Walter Landauer,  

 

期刊: Teratology  (WILEY Available online 1976)
卷期: Volume 13, issue 1  

页码: 41-46

 

ISSN:0040-3709

 

年代: 1976

 

DOI:10.1002/tera.1420130108

 

出版商: Wiley Subscription Services, Inc., A Wiley Company

 

数据来源: WILEY

 

摘要:

AbstractThe amino acids γ‐aminobutyric acid, taurocholate, guanidine, glycine, and β‐alanine, known to have putative functions as neurotransmitters, when given as supplement to carbachol or decamethonium, greatly reduced the incidence of malformations produced in chicken embryos by these depolarizing cholinomimetic teratogens. In combination with the nondepolarizing teratogens neostigmine and pyridostigmine similarly beneficial effects occurred only by supplementation with γ‐aminobuty

 

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