Identification and control of muscle-relaxant anaesthesia
作者:
D.A.Linkens,
A.J.Asbury,
S.J.Rimmer,
M.Menad,
期刊:
IEE Proceedings D (Control Theory and Applications)
(IET Available online 1982)
卷期:
Volume 129,
issue 4
页码: 136-141
年代: 1982
DOI:10.1049/ip-d.1982.0027
出版商: IEE
数据来源: IET
摘要:
Systems identification trials are described for determining the dynamics involved in drug-induced paralysis. The aim is to provide automatic control of levels of muscle relaxation in anaethetised patients undergoing surgery. A linearised model has been successfully identified giving combined pharmacokinetic and pharmacodynamic parameters. The-model has implications for the design of feedback controllers, and simulations involving the use of Smith predictors are presented. Feedforward control is also considered to allow for perturbations in paralysis caused by general anaesthetic drugs used to induce unconsciousness.
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