Immunological studies of sporidesmin: Production of antibodies to azo-linked derivatives of 2-amino-5-chloro-3,4-dimethoxy benzyl alcohol
作者:
W.E. Jonas,
A.F. Erasmuson,
期刊:
New Zealand Veterinary Journal
(Taylor Available online 1977)
卷期:
Volume 25,
issue 6
页码: 161-164
ISSN:0048-0169
年代: 1977
DOI:10.1080/00480169.1977.34392
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
2-Amino-5-chloro-3,4-dimethoxy benzyl alcohol (ACD-MBA), a compound similar to part of the substituted tryptophan in the sporidesmin molecule was synthetized. It was coupled to bovinegamma-globulin through azo linkages and used to immunize guinea-pigs and rabbits or coupled to various bacteria and used to immunize guinea-pigs. Antibodies to ACDMBA were demonstrated by a complement fixation test. Hapten-inhibition of complement fixation showed that the anti-ACDMBA antibodies cross-reacted with sporidesmin and some derivatives of sporidesmin.
点击下载:
PDF (528KB)
返 回