首页   按字顺浏览 期刊浏览 卷期浏览 In-situ-Isolated Perfused Rat Pancreas: a New Method for Pharmacological Studies of the...
In-situ-Isolated Perfused Rat Pancreas: a New Method for Pharmacological Studies of the Exocrine Pancreas

 

作者: R. Tournut,   A. Estival,   N. Vaysse,   J.P. Pascal,   A. Ribet,  

 

期刊: Digestion  （Karger Available online 1977）
卷期: Volume 15, issue 4  

页码: 329-337

 

ISSN:0012-2823

 

年代: 1977

 

DOI:10.1159/000198019

 

出版商: S. Karger AG

 

关键词: Bicarbonates;Gastrointestinal hormones;Pancreas;Pancreatic juice;Proteins;Rats

 

数据来源: Karger

 

摘要:

A method of in-situ-isolated perfused rat pancreas is described. In situ perfusion of the isolated rat pancreas allows a faster set-up, thanks to a simpler operating procedure. The sensitivity of the isolated rat pancreas has been tested with secretin and cholecystokinin. The pancreas responds to doses of secretin as low as 0.005 CU/kg·h. Such a highly sensitive model might prove to be useful for the bioassay of secretin and the study of the effects of pancreatic secretagogues

 

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