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Association between Alpha-1-Antitrypsin Types and the Common Cold

 

作者: N.G. Martin,   J.G. Oakeshott,   P. Clark,   A. Carr,  

 

期刊: Human Heredity  （Karger Available online 1983）
卷期: Volume 33, issue 5  

页码: 265-269

 

ISSN:0001-5652

 

年代: 1983

 

DOI:10.1159/000153389

 

出版商: S. Karger AG

 

关键词: α1-Antitrypsin;Common cold;Pitypes;Genetic association

 

数据来源: Karger

 

摘要:

Associations have been found between self-reported cold symptoms and Pi type in 84 pairs of identical twins. The risk of cold symptoms relative to MM phenotypes was 1.2 times greater in MS and 2.5 times greater in MZ individuals. Up to 9% of variance in cold symptoms could be attributed to Pi type, representing at least 20% of the total genetical variance.

 

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