SUMMARY1. In 1963, 7,644 patients in the United States in the 5–60 year age group died from “nephritis and nephrosis” in its various forms and from “infections of the kidney.” In the same year, 1,406 patients in the same age group died of primary hepatobiliary malignancy, and 13,601 patients died of “cirrhosis”. 2. Generally accepted contraindications to kidney transplantation in patients with non-neoplastic fatal renal disease (age less than 60), include irreversible lesions of brain, heart, or lungs, severe urinary sepsis, or advanced iliac arteriosclerosis. Unfortunately data for incidence of these lesions in potential recipients are not available. Candidates for liver transplantation very often will be disqualified either because of distant metastatic spread if they have hepatic malignancy, or because of unreliability in following a program of immunosuppression, if they are alcoholic. The number of potential liver recipients in the United States in 1963 was about 4000. 3. From the above data, it appears that the best cadaver donors, i.e., patients dying with subarachnoid hemorrhage, would have been able to supply, if no logistic or legal problems existed, about 10,600 kidneys to the approximately 7,600 potential kidney recipients, and about 6,000 livers to the approximately 4,000 potential liver recipients. 5. If additional kidney and liver donors can also be found among other groups of patients dying with central nervous system lesions, it becomes more clear that efficient logistic techniques and legal codes should make it possible for all transplanted kidneys and livers to be harvested from the recently deceased.