Failure of Medullary Carcinoma of the Thyroid to Respond to Doxorubicin Therapy
作者:
Muhammed Husain,
Robert N. Alsever,
Paul Lock,
Walter F. George,
Fred H. Katz,
期刊:
Hormone Research in Paediatrics
(Karger Available online 1978)
卷期:
Volume 9,
issue 1
页码: 22-25
ISSN:1663-2818
年代: 1978
DOI:10.1159/000178893
出版商: S. Karger AG
关键词: Medullary carcinoma of thyroid gland;Doxorubicin chemotherapy;Calcitonin
数据来源: Karger
摘要:
We describe 3 patients with metastatic medullary carcinoma of the thyroid who were treated with doxorubicin hydrochloride (Adriamycin). Serum calcitonin was measured before and after doxorubicin therapy. Doxorubicin failed to arrest the progression of the disease in any of the patients. Although serum calcitonin levels dropped in 1 patient during therapy, they remained markedly elevated in all 3 patients. From the present series it appears that medullary thyroid carcinoma often does not have a response to doxorubicin.
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