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Failure of Medullary Carcinoma of the Thyroid to Respond to Doxorubicin Therapy

 

作者: Muhammed Husain,   Robert N. Alsever,   Paul Lock,   Walter F. George,   Fred H. Katz,  

 

期刊: Hormone Research in Paediatrics  (Karger Available online 1978)
卷期: Volume 9, issue 1  

页码: 22-25

 

ISSN:1663-2818

 

年代: 1978

 

DOI:10.1159/000178893

 

出版商: S. Karger AG

 

关键词: Medullary carcinoma of thyroid gland;Doxorubicin chemotherapy;Calcitonin

 

数据来源: Karger

 

摘要:

We describe 3 patients with metastatic medullary carcinoma of the thyroid who were treated with doxorubicin hydrochloride (Adriamycin). Serum calcitonin was measured before and after doxorubicin therapy. Doxorubicin failed to arrest the progression of the disease in any of the patients. Although serum calcitonin levels dropped in 1 patient during therapy, they remained markedly elevated in all 3 patients. From the present series it appears that medullary thyroid carcinoma often does not have a response to doxorubicin.

 

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