Trimethoprim-Sulphamethoxazole in the Treatment of Cholera
作者:
G. Pastore,
G. Rizzo,
G. Fera,
O. Schiraldi,
期刊:
Chemotherapy
(Karger Available online 1977)
卷期:
Volume 23,
issue 2
页码: 121-128
ISSN:0009-3157
年代: 1977
DOI:10.1159/000221980
出版商: S. Karger AG
关键词: Vibrio Ogawa E1 Tor;Cholera patients;Antibacterial treatment;TM-SMX;Chloramphenicol;Tetracycline;Cholera carriers
数据来源: Karger
摘要:
67 of the bacteriologically proved adult acute cholera patients have been examined in order to evaluate the efficacy of TM-SMX in comparison with tetracycline and chloramphenicol in the eradication of Vibrio cholerae from stools. Our results demonstrated that all three drugs sterilized the stools of all patients within 3 days with the exception of one case of TM-SMX’s group, which had negative culture stools after 4 days. On the basis of our experience it can be emphasized that TM-SMX can support chloramphenicol and tetracycline in the antibacterial treatment of cholera with the advantage that the drug is efficacious with daily administration
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