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Hemostatic Effect of Transfused Willebrand Factor in Porcine von Willebrand’s Disease

 

作者: E.J.W. Bowie,   D.N. Fass,   C.A. Owen, Jr.,  

 

期刊: Pathophysiology of Haemostasis and Thrombosis  （Karger Available online 1980）
卷期: Volume 9, issue 6  

页码: 352-365

 

ISSN:1424-8832

 

年代: 1980

 

DOI:10.1159/000214377

 

出版商: S. Karger AG

 

关键词: Hemostasis;Willebrand factor;von Willebrand’s disease;Porcine von Willebrand’s disease

 

数据来源: Karger

 

摘要:

Cryoprecipitate was infused into pigs with severe von Willebrand’s disease, and the bleeding time was corrected when the plasmatic level of VIII R:AG (WF) was above 30 U/dl. The VIII R:AG (WF) was not completely recovered but none was found in the plasma or endothelial cells. A new method for measuring the bleeding time is described -the ratio bleeding time. These results in pigs are compared with the reported results in human

 

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