Silica beads of 6μm average diameter were silanized with methylvinyldiethoxysilane and then coated with phenyl-vinylmethylpolysiloxane. The chromatography (RP-HPLC) with the prepared material has superior ability for the separation of polar, non-polar and basic compounds. The chromatographic peaks are symmetric. Its stability has been studied. After continuous use for four months, the carbon content and chromatographic behavior of the phase were unchanged.