AbstractThis paper summarizes major research achievements concerning the understanding and control of aggression and destructive violence, seen in the contexts of evolution (both biological and cultural) and systems theory. Agonistic behavior, defined as behavior functional in situations of conflict between species mates, most probably evolved out of the function of defensive behavior but has since acquired a variety of other adaptive functions as well as the potential for destructive dysfunction. Recent research demonstrates the importance of culture in regulating human agonistic behavior, directing it toward either useful functions or destructive violence. Among advanced industrial nations, the United States has the most severe problems with violence as measured by homicide and murder rates. Similar but more extreme variation can be found among tribal societies. It is through cultural change that the available scientific information concerning improved methods for directing agonistic behavior into positive and beneficial channels must be achieved. Therefore, major emphasis should be placed on research dealing with human cultural evolution. The science of bringing about desirable social change is still in its infancy.