The Effect of Aspartame on Migraine Headache
作者:
Shirley M. Koehler,
Alan Glaros,
期刊:
Headache: The Journal of Head and Face Pain
(WILEY Available online 1988)
卷期:
Volume 28,
issue 1
页码: 10-14
ISSN:0017-8748
年代: 1988
DOI:10.1111/j.1365-2524.1988.hed2801010.x
出版商: American Association for the Study of Headache/Blackwell Science Ltd
数据来源: WILEY
摘要:
SYNOPSISRecently, three pilot studies have proposed that the addition of products containing aspartame to thediets of migraine headache sufferers may produce a significant increase in the frequency of theirmigraines. The present study was a controlled thirteen‐week, double‐blind, randomized cross‐over studycomparing the effect of aspartame to that of a matched placebo on the frequency and intensity of migraineheadache. The results of this study indicated that the ingestion of aspartame by migraineurs caused asignificant increase in headache frequency for some subjects. The implications of these findings andsuggestions for further research are disc
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