Retinal Capillary Hemodynamics and VEP/Pressure Tolerance: Evidence of Retinal Microcirculatory Compromise in Treated Glaucomatous Eyes
作者:
William E. Sponsel,
Sandy R. Zetlan,
Richard Stodtmeister,
Paul L. Kaufman,
期刊:
Ophthalmologica
(Karger Available online 1997)
卷期:
Volume 211,
issue 3
页码: 172-177
ISSN:0030-3755
年代: 1997
DOI:10.1159/000310785
出版商: S. Karger AG
关键词: Intraocular pressure;Glaucoma;Visual-evoked potential;Retinal circulation;Leukocyte velocity;Blue field entoptic phenomenon
数据来源: Karger
摘要:
Measurements of retinal leukocyte velocity were made in single eyes of 6 glaucomatous adults and 9 normal subjects at each of 4 discrete levels of IOP elevation assigned according to the characteristics of prior pattern-evoked cortical potential pressure tolerance measurements. Glaucomatous eyes failed to demonstrate any stabilization in retinal leukocyte velocity at pressures above 45 mm Hg, with velocities 33% lower than normal for a comparable degree of IOP elevation (p < 0.012). Even at baseline IOP, leukocyte velocity was 27.2% slower in the treated glaucomatous eyes than in normal control eyes (p≤ 0.013), despite comparable baseline IOP levels in both groups.
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