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Characterization of Human Glioblastoma Cell Lines in vitro and their Xenografts in Nude Mice by DNA Fingerprinting

 

作者: Ö. Türeci,   H. Fischer,   P. Lagoda,   O.-G. Issinger,  

 

期刊: Onkologie  （Karger Available online 1990）
卷期: Volume 13, issue 4  

页码: 305-308

 

ISSN:0378-584X

 

年代: 1990

 

DOI:10.1159/000216781

 

出版商: S. Karger GmbH

 

关键词: Human glioma;Nude mouse;DNA fingerprinting;Hypervariable multilocus probes;Cell line stability

 

数据来源: Karger

 

摘要:

Human gliomas were grown as permanent tissue cultures and xenografts in nude mice. DNA fingerprint patterns from two human gliomas were established using two different hypervariable multilocus probes ([GTG]5 and 33.15). In general the cell lines investigated showed an overall stability in the DNA fingerprint pattern. However, differences in the DNA fingerprint patterns were shown to occur depending upon the above mentioned parameters.

 

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