首页   按字顺浏览 期刊浏览 卷期浏览 Renal Cell Carcinoma – Xenotransplantation into Immunosuppressed Mice
Renal Cell Carcinoma – Xenotransplantation into Immunosuppressed Mice

 

作者: L. Kopper,   E. Magyarosy,   P. Nagy,   K. Lapis,   I. Számel,   S. Eckhardt,   S. Csata,   G. Wabrosch,   D. Répássy,  

 

期刊: Oncology  （Karger Available online 1984）
卷期: Volume 41, issue 1  

页码: 19-24

 

ISSN:0030-2414

 

年代: 1984

 

DOI:10.1159/000225784

 

出版商: S. Karger AG

 

关键词: Human tumor xenografts;Renal cell carcinoma;Chemotherapy;Estrogen receptor

 

数据来源: Karger

 

摘要:

21 human renal cell carcinomas (RCC) were xenotransplanted into artificially immunosuppressed mice. 4 tumors grew successfully retaining some characteristics of the primary tumors (according to morphology and karyotype analysis), but losing metastatic capacity. One of the serially transplantable tumors (HT 40) with hyperdiploid cellular DNA content and estrogen receptor positivity failed to respond to the single maximally tolerated dose of several cytotoxic agents.

 

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