Regulation of Carcinogens
作者:
Edmund Crouch,
Richard Wilson,
期刊:
Risk Analysis
(WILEY Available online 1981)
卷期:
Volume 1,
issue 1
页码: 47-57
ISSN:0272-4332
年代: 1981
DOI:10.1111/j.1539-6924.1981.tb01355.x
出版商: Blackwell Publishing Ltd
关键词: risk assessment;carcinogens;carcinogenic potency;regulation
数据来源: WILEY
摘要:
We propose a procedure, suitable for regulatory use, for estimating individual and societal risks of carcinogenic materials by using information on interspecies comparisons of carcinogenic potency. The consistent treatment of uncertainties allows evaluation of confidence limits and hence regulatory measures of risk which incorporate safety factors and incentives for better information. Numerical examples are given, together with discussion of the treatment of undetected carcinogens. Applications of the procedure to setting priorities for carcinogenicity testing and to product substitution are mentioned.
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