HYPERCALCAEMIA IN ASSOCIATION WITH RENAL FAILURE: THE ROLE OF IMMOBILISATION
作者:
R. L. PRINCE,
J. A. EISMAN,
R. W. SIMPSON,
期刊:
Australian and New Zealand Journal of Medicine
(WILEY Available online 1983)
卷期:
Volume 13,
issue 1
页码: 8-10
ISSN:0004-8291
年代: 1983
DOI:10.1111/j.1445-5994.1983.tb04537.x
出版商: Blackwell Publishing Ltd
关键词: Hypercalcaemia;renal failure;immobilisation;1,25 dihydroxy vitamin D3;parathyroid hormone
数据来源: WILEY
摘要:
Abstract:Hypercalcaemia occurring after ten weeks of immobilisation was observed in four adult patients all of whom had had prior renal failure sufficient to require renal dialysis. In all patients parathyroid hormone levels were normal or low and in three plasma 1,25(OH)2D3levels were low. These findings are consistent with immobilisation induced increases in bone calcium resorption. Renal excretion of calcium may have been impaired by renal dysfunction resulting in hypercalcaemia and suppression of plasma PTH and 1,25(OH)2D3levels. Resolution of the hypercalcaemia was associated with remobilisation. Parathyroidectomy is inappropriate treatment.
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