Serum cholesterol levels were measured in 101 young male psychiatric inpatients with nonpsychotic disorders. When the patients were divided into those with antisocial personality, with alcoholism, with drug abuse and with other disorders, there was no overall difference in cholesterol level by group. Specifically there was no significant difference between the 24 patients whose primary diagnosis was antisocial personality and the 43 who had other personality disorders, neuroses or adjustment reactions. The data did not support an earlier report that lower serum cholesterol levels were characteristic of men with antisocial personality.