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Natural Killer Cell Activity in Early Human Pregnancy

 

作者: M. Opsahl,   K. Hansen,   T. Klein,   D. Cunningham,  

 

期刊: Gynecologic and Obstetric Investigation  （Karger Available online 1994）
卷期: Volume 37, issue 4  

页码: 226-228

 

ISSN:0378-7346

 

年代: 1994

 

DOI:10.1159/000292564

 

出版商: S. Karger AG

 

关键词: Natural killer cells;Pregnancy;Spontaneous abortion;Maternal immunity

 

数据来源: Karger

 

摘要:

Natural killer (NK) cell activity was determined in 41 women during the first trimester of pregnancy. NK cytotoxicity was similar between the study subjects and nonpregnant controls and was not a reflection of a change in the circulating number of cells or density in culture. Although NK cells may play a role in maternal immune status in advanced pregnancy, NK cells do not appear to be crucially involved in the first trimester, when reproductive wastage usually occurs.

 

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