Dermatopharmacology of Salicylic Acid
作者:
Erich G. Weirich,
Josef K. Longauer,
Alan H. Kirkwood,
期刊:
Dermatology
(Karger Available online 1976)
卷期:
Volume 152,
issue 2
页码: 87-99
ISSN:1018-8665
年代: 1976
DOI:10.1159/000251167
出版商: S. Karger AG
关键词: Dermatopharmacology;salicylic acid;Salicylic acid;local antiphlogistics and corticoids;Topical contra-inflammatory effect
数据来源: Karger
摘要:
The acute contra-inflammatory effects of salicylic acid, three standard dermatocorticoids and four contact antiphlogistics have been investigated by means of a UV dermatitis inhibition test in the guinea pig. The substances tested had a distinct inhibitory effect on the development of erythema and can be ranked in the following ascending order of activity (percent of maximum possible score): bufexamac = 36%, salicylic acid = 37%, hydrocortisone = 44%, acetylsalicylic acid = 48%, flumethasone pivalate = 51%, fluocinolone acetonide = 52%, phenylbutazone = 56%, and indomethacin = 58%.
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