The effect of total body microwave hyperthermia and hepatic artery ligation on liver tumors—an experimental study in rats
作者:
Goran Carlsson,
Larsolof Hafström,
Anders Hugander,
Per‐Ebbe Jönsson,
Magnus Bolmsjö,
Bertil Persson,
期刊:
Journal of Surgical Oncology
(WILEY Available online 1983)
卷期:
Volume 22,
issue 1
页码: 37-40
ISSN:0022-4790
年代: 1983
DOI:10.1002/jso.2930220110
出版商: Wiley Subscription Services, Inc., A Wiley Company
关键词: liver tumor;hyperthermia;microwaves;hepatic artery ligation
数据来源: WILEY
摘要:
AbstractThe effect of general microwave hyperthermia and hepatic artery ligation (HAL) was tested on Wistar rats with a transplanted N‐methyl‐N‐nitroso‐guanidine‐induced adenocarcinoma in the liver. Total body hyperthermia (41.5°C for 1 hour, three times during 24 hours) was given on the same day as HAL, and 1, 2, and 3 days after. HAL induced a slower tumor growth than untreated controls. No additive effect was registered when total body microwave hyperthermia was added to HAL. When hyperthermia was added 2 days after HAL, there was a transient decrease in tumor volume as in the HAL series. Total body microwave hyperthermia added 3 days after HAL induced a faster tumor growth than after HAL alone. When hyperthermia was added the same day and 1 day after HAL, there was a 50%
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