Circulating Anticoagulant against Factor XII in Smoldering Leukemia
作者:
J.R. Duran-Suarez,
M. Vila,
S. Rodriguez-Bueno,
J. Triginer,
期刊:
Acta Haematologica
(Karger Available online 1982)
卷期:
Volume 67,
issue 2
页码: 128-131
ISSN:0001-5792
年代: 1982
DOI:10.1159/000207039
出版商: S. Karger AG
关键词: Circulating anticoagulant;Factor XII;Smoldering leukemia
数据来源: Karger
摘要:
A circulating anticoagulant against factor XII was detected in a patient with smoldering leukemia. Despite severe associated thrombocytopenia the patient suffered two thromboembolic episodes, besides mucosal bleeding. The circulating anticoagulant was demonstrated not only in the plasma but also in the serum. Its activity was not affected by heating at 56° C for 30 min and it was not adsorbed by S04Ba or A1(OH)3. The circulating anticoagulant was not dializable and demonstrated to be an IgG. This is apparently the first reported association of smoldering leukemia and a circulating anticoagulant against factor XII
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