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On some derivatives of ferrocene, novel acetylcholinesterase inhibitors

 

作者: Bogumil Hetnarski,   Abel Lajtha,   Henryk M. Wisniewski,  

 

期刊: Journal of Neuroscience Research  （WILEY Available online 1980）
卷期: Volume 5, issue 1  

页码: 1-5

 

ISSN:0360-4012

 

年代: 1980

 

DOI:10.1002/jnr.490050102

 

出版商: Wiley Subscription Services, Inc., A Wiley Company

 

关键词: metallocenes;ferrocene;oximes;methylcarbamates;ferrocenylcarboxaldehyde;derivatives;activity;inhibition;acetylcholinesterase

 

数据来源: WILEY

 

摘要:

AbstractEight novel methylcarbamates, derivatives of ferrocenylketoximes and aldoximes, and ferrocenyl‐p‐hydroxyphenylaldimine were prepared. They are the first carbamates in the field of ferrocene derivaties. Their anticholinesterase activity was tested and found to fall in the range of 10−4through 10−6M (I50). The correlation between the activity of the compounds and the kind of substitutents grafted on the methylene carbon atom is di

 

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