Taxanes in ovarian cancer treatment
作者:
Kasan Seetalarom,
Andrzej Kudelka,
Claire Verschraegen,
John Kavanagh,
期刊:
Current Opinion in Obstetrics and Gynecology
(OVID Available online 1997)
卷期:
Volume 9,
issue 1
页码: 14-20
ISSN:1040-872X
年代: 1997
出版商: OVID
数据来源: OVID
摘要:
Paclitaxel and docetaxel are active in the treatment of patients with advanced ovarian cancer. The taxanes in various dose schedules achieve response rates of 10–50% with a median overall survival of 10–12 months in patients with platinum-refractory disease. Paclitaxel has activity in chemotherapy-naive patients when administered alone or in combination with platinum. The role of intraperitoneal paclitaxel remains to be defined.
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