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Aplastic Anemia after Prolonged Ingestion of Indomethacin

 

作者: A. Kornberg,   E.A. Rachmilewitz,  

 

期刊: Acta Haematologica  （Karger Available online 1982）
卷期: Volume 67, issue 2  

页码: 136-138

 

ISSN:0001-5792

 

年代: 1982

 

DOI:10.1159/000207041

 

出版商: S. Karger AG

 

关键词: Aplastic anemia;Indomethacin

 

数据来源: Karger

 

摘要:

Two rare cases of aplastic anemia after prolonged ingestion of indomethacin are described. One patient recovered spontaneously within several weeks following discontinuation of the drug while the second one died. The aplastic anemia may be related to the inhibitory effect of indomethacin on prostaglandins and cyclic nucleotides which have a regulatory role in erythropoiesis and myelopoiesis.

 

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