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Immune Complex Disease Associated with Peroben® Intake

 

作者: D. van Neste,   G.E. Piérard,   J.F. Hermanns,  

 

期刊: Dermatology  (Karger Available online 1979)
卷期: Volume 158, issue 6  

页码: 417-426

 

ISSN:1018-8665

 

年代: 1979

 

DOI:10.1159/000250792

 

出版商: S. Karger AG

 

关键词: Drug-induced lupus syndrome;Peroben®;Immune complex disease;Clq binding;Leukocytoclastic vasculitis

 

数据来源: Karger

 

摘要:

The clinical history and biological investigations of a patient presenting an immune complex disease induced by Peroben® are reported. Biological signs were those of a drug-induced lupus syndrome. A provocation test allowed disclosure of its pathomechanism, since during Peroben intake a high Clq binding activity occurred and later regressed, while deposits of IgM and C3 were evidenced in the vessel walls. Complete or partial thrombosis succeeded accompanying a leukocytoclastic vasculitis

 

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