Immune Complex Disease Associated with Peroben® Intake
作者:
D. van Neste,
G.E. Piérard,
J.F. Hermanns,
期刊:
Dermatology
(Karger Available online 1979)
卷期:
Volume 158,
issue 6
页码: 417-426
ISSN:1018-8665
年代: 1979
DOI:10.1159/000250792
出版商: S. Karger AG
关键词: Drug-induced lupus syndrome;Peroben®;Immune complex disease;Clq binding;Leukocytoclastic vasculitis
数据来源: Karger
摘要:
The clinical history and biological investigations of a patient presenting an immune complex disease induced by Peroben® are reported. Biological signs were those of a drug-induced lupus syndrome. A provocation test allowed disclosure of its pathomechanism, since during Peroben intake a high Clq binding activity occurred and later regressed, while deposits of IgM and C3 were evidenced in the vessel walls. Complete or partial thrombosis succeeded accompanying a leukocytoclastic vasculitis
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