Effect of Tiopronin on Senile Cataracts
作者:
H. Ichikawa,
K. Imaizumi,
Y. Tazawa,
Y. Obara,
Y. Ishikawa,
I. Tobari,
Y. Tanabe,
期刊:
Ophthalmologica
(Karger Available online 1980)
卷期:
Volume 180,
issue 5
页码: 293-298
ISSN:0030-3755
年代: 1980
DOI:10.1159/000308990
出版商: S. Karger AG
数据来源: Karger
摘要:
The therapeutic effect of tiopronin on incipient senile cataracts was evaluated in 150 cases (275 eyes) by a double-blind study using nonactive placebo. A more favorable tendency to visual acuity was noted in the tiopronin than in the placebo group. The slit-lamp microscopic findings showed a statistically significant difference between the tiopronin and the placebo groups. Integrated judgement revealed tiopronin to be significantly effective as compared with the placebo. A side effect of fever with systemic eruption was observed in 1 case in the tiopronin group but disappeared completely when administration of the drug was discontinued.
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